Is SIMPONI the same as methotrexate?

Otrexup (methotrexate) is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Calms down the immune system. Simponi (golimumab) effectively calms down your immune system, but it is given as a shot and puts you at risk of serious infections like tuberculosis or hepatitis B.

Does SIMPONI cause weight gain?

Sudden weight gain (gaining 3 to 5 pounds over a day or two) can be a symptom of new or worsening heart failure. Other medications that may be used to treat the same conditions as Simponi and Simponi Aria may cause weight gain.

Is SIMPONI better than Humira?

Humira has an average rating of 6.2 out of 10 from a total of 655 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 33% reported a negative effect. Simponi has an average rating of 6.2 out of 10 from a total of 100 ratings on Drugs.com.

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How long is golimumab Effective?

Eighty-two (43.0%) patients needed dose escalation from 50 to 100 mg every 4 weeks during follow-up, with a mean time until intensification of 8.03 ± 8.64 months. Finally, golimumab maintenance therapy had a mean duration of almost 18 months. Golimumab was discontinued in almost 60% of patients during the follow-up.

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What is the generic name for golimumab?

Golimumab is a type of drug known as a biological therapy. It's also known by the brand name Simponi. In rheumatoid arthritis and some other inflammatory conditions, too much of a protein called tumour necrosis factor (TNF) is produced by the immune system. This can cause inflammation, pain and damage to your joints.

Is SIMPONI the same AS methotrexate?

Otrexup (methotrexate) is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Calms down the immune system. Simponi (golimumab) effectively calms down your immune system, but it is given as a shot and puts you at risk of serious infections like tuberculosis or hepatitis B.

What is another name for SIMPONI?

Golimumab is a type of drug known as a biological therapy. It's also known by the brand name Simponi. In rheumatoid arthritis and some other inflammatory conditions, too much of a protein called tumour necrosis factor (TNF) is produced by the immune system. This can cause inflammation, pain and damage to your joints.

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What is an alternative drug to methotrexate?

Leflunomide (Arava®) Leflunomide is also an effective DMARD. Its efficacy is similar to methotrexate in terms of signs and symptoms, and is a viable alternative to patients who have failed or are intolerant to methotrexate.

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What type of drug is SIMPONI?

What is Golimumab (Simponi®)? Golimumab is in a class of drugs called biologics. Golimumab is a treatment for adults with moderate to severe rheumatoid arthritis, active psoriatic arthritis, or active ankylosing spondylitis.

Do biologics work better methotrexate?

Many people never need biologic DMARDs because conventional DMARDs control their disease well. The American College of Rheumatology recommends methotrexate over a biologic as the first choice for most people with inflammatory autoimmune diseases like rheumatoid arthritis and psoriatic arthritis.

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Which biologic is best for rheumatoid arthritis?

Biological treatments, such as adalimumab, etanercept and infliximab, are a newer form of treatment for rheumatoid arthritis. They're usually taken in combination with methotrexate or another DMARD, and are usually only used if DMARDs have not been effective on their own. Biological medicines are given by injection.

What are the side effects of SIMPONI?

  • infections, cold or flu symptoms;
  • abnormal liver function tests;
  • high blood pressure;
  • rash; or.
  • pain, itching, redness, or swelling where the medicine was injected.
  • Does SIMPONI cause depression?

    In clinical trials, serious depression including suicidality has been reported in patients treated with SIMPONI. Depression has also been reported in the postmarketing setting and is described in published medical literature.

    Can you drink with SIMPONI?

    Alcohol. There's no known interaction between golimumab and alcohol, so it's fine to have a drink if you're taking this medication.

    How does SIMPONI compare with Humira?

    Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects. Calms down the immune system. Simponi (golimumab) effectively calms down your immune system, but it is given as a shot and puts you at risk of serious infections like tuberculosis or hepatitis B.

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    How long does it take SIMPONI to work?

    Simponi can take about 2 weeks before patients start to feel its effects. Some patients notice a benefit shortly after their first dose, while in others it can take several weeks. It can take 4 to 12 weeks before patients feel a lot of benefit.

    What is the difference between golimumab and adalimumab?

    Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects. Calms down the immune system. Simponi (golimumab) effectively calms down your immune system, but it is given as a shot and puts you at risk of serious infections like tuberculosis or hepatitis B.

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